Why?

Science can naturally lead people to grapple with their existence, and questions of meaning and purpose.
John Archibald Wheeler was one of the most influential theoretical physicists of the 20th century. He was a collaborator of Einstein and Bohr, and the Ph.D supervisor of Richard Feynman. He coined the terms "black hole'' and wormhole. Wheeler both began and ended his autobiography with these questions:

How come the quantum?
How come existence?"

Geons, Black Holes, & Quantum Foam: A Life in Physics
by John Archibald Wheeler with Kenneth Ford: W.W. Norton, 1998

Wheeler came to some strange conclusions, whether they are viewed from a scientific, philosophical, or theological perspective. But, his life clearly illustrates how science (success, failures, and paradoxes) drives us to ask "Why?" questions.